Clinical Trial Endpoints in DLBCL

Key endpoints in DLBCL clinical trials

  • Overall survival (OS): The time from randomization in a clinical trial until death from any cause30
  • Progression-free survival (PFS): The time from randomization in a clinical trial until progression or death. PFS is an endpoint in many ongoing clinical trials30
  • Event-free survival (EFS): The time from study entry until any treatment failure, including disease progression, treatment discontinuation for any reason, or death31
  • Overall response rate (ORR): The sum of the percentage of patients who achieve complete and partial responses30
  • Duration of response (DoR): The time from achieving a response until relapse or disease progression31