What's New?

As of May 2013

Research Education Updates:

Research Cancer Immunotherapy

Learn more about the potential of PD-L1 inhibition and cancer immunotherapy.

Research Cancer Immunotherapy

Research B-cell

Updated the site to include more information about Glycoengineering.

Research B-cell
Pipeline Molecules Updates:

Pipeline Overview: Content Update

For more information about molecules in early-and late stage development download the new brochure.

Gene Takeaway Card

Anti-PDL1 (MPDL3280A)

Anti-PDL1 targets, a protein expressed on the surface of cancer cells. Find out how this molecule was designed to help promote anti-tumor immune activity.

Anti-PDL1

Anti-CD22 ADC (DCDT2980S)

The Anti-CD22 ADC is composed of a MAb, a stable linker, and a cytotoxic. Find out how this molecule may selectively target B-cells expressing CD22.

Anti-CD22

Anti-CD79b ADC (DCDS4501A)

The Anti-CD79b ADC is composed of a MAb, a stable linker, and a cytotoxic. Find out how this molecule may selectively bind to CD79b and minimize effects on normal cells.

Anti-CD79b
Therapeutic Targets Updates:

Targeting CD22

Learn more about CD22, a cell surface protein that is only expressed on B-cells.

Targeting CD22

Targeting CD79b

Find out about CD79b, a key component of the B-cell receptor, and its role in malignant B-cell signaling.

Targeting CD79b

Updated Video Narrations:

Biological Pathways: HER signaling: Updated Video

Biological Pathways: Apoptotic pathways: Updated Video

Biological Pathways: MAPK signaling: Updated Video

Biological Pathways: PI3K signaling: Updated Video

Biological Pathways: Angiogenic signaling: Updated Video

As of December 2012

Pipeline Update

Anti-HER3/EGFR MAb (MEHD7945A) was added to the Genentech Pipeline.

Pipeline Molecules