At Genentech BioOncology, we drive cancer research forward by exploring innovative ways to target the biological mechanisms
of cancer. We specifically design molecules so they can selectively bind to a therapeutic target that regulates growth, proliferation,
and cell survival.
Discover how Akt plays a central role in cancer cell growth and survival.
Learn more about how targeting BCL-2 may help lead to apoptosis in cancer cells.
Find out about CD79b, a key component of the B-cell receptor, and its role in malignant B-cell signaling.
Discover more about the role of HER1 in multiple tumor types.
Examine the role of HER3, a key HER family receptor directly involved in the activation of the PI3K pathway.
Find out whether this HER family member plays a role in cancer development.
Discover more about how tumor cell proliferation may be prevented by targeting MEK.
Find out how the mTOR kinase acts as a signaling nodal point in promoting the growth and survival of cancer cells.
Learn more about the biological effects of targeting PI3K in tumor cells.