References:

You can view the abstracts for the references listed below via the National Library of Medicine's PubMed service. Just click the PubMed links. Click here to view the PubMed disclaimer and copyright notice.

1.: Von Hoff DD, LoRusso PM, Rudin CM, et al. Inhibition of the hedgehog pathway in advanced basal-cell carcinoma. N Engl J Med. 2009;361:1164-1172.
Link to abstract on PubMed
2.: Williams JA. Hedgehog signaling pathway as a target for therapeutic intervention in basal cell carcinoma. Drug News Perspect. 2003;16:657-662.
Link to abstract on PubMed
3.: Binns W, James LF, Shupe JL, Everett G. A congenital cyclopean-type malformation in lambs induced by maternal ingestion of a range plant, Veratrum californicum. Am J Vet Res. 1963;24:1164-1175.
Link to abstract on PubMed
4.: Cooper MK, Porter JA, Young KE, Beachy PA. Teratogen-mediated inhibition of target tissue response to Shh signaling. Science. 1998;280:1603-1607.
Link to abstract on PubMed
5.: Incardona JP, Gaffield W, Kapur RP, Roelink H. The teratogenic Veratrum alkaloid cyclopamine inhibits sonic hedgehog signal transduction. Development. 1998;125:3553-3562.
Link to abstract on PubMed
6.: Robarge KD, Brunton SA, Castanedo GM. GDC-0449—a potent inhibitor of the hedgehog pathway. Bioorg Med Chem Lett. 2009;19:5576-5581.
Link to abstract on PubMed
7.: Scales SJ, de Sauvage FJ. Mechanisms of Hedgehog pathway activation in cancer and implications for therapy. Trends Pharmacol Sci. 2009;30:303-312.
Link to abstract on PubMed