At Genentech BioOncology, we are on the cutting edge of cancer research, as evidenced by our robust product pipeline of innovative molecules designed to target cancer through specific molecular processes.
Select any of the pipeline molecules below or filter by Tumor Type to learn more.
- Other Tumor Types
- Solid Tumors
Akt Inhibitor (GDC-0068)
Learn more about the mechanisms by which the Akt Inhibitor GDC-0068 may promote apoptosis and growth arrest in cancer cells.
Anti-CD22 ADC (DCDT2980S)
The anti-CD22 ADC is composed of a MAb, a stable linker, and a cytotoxic. Find out how this molecule may selectively target B-cells expressing CD22.
Anti-CD79b ADC (DCDS4501A)
The anti-CD79b ADC is composed of a MAb, a stable linker, and a cytotoxic. Find out how this molecule may selectively bind to CD79b and minimize effects on normal cells.
Anti-HER3/EGFR MAb (MEHD7945A)
Anti-HER3/EGFR is a MAb with dual binding specificity. Learn how targeting 2 receptors simultaneously may inhibit multiple cancer signaling pathways.
Anti-PDL1 targets PD-L1, a protein expressed on the surface of cancer cells. Find out how this molecule was designed to help promote anti-tumor immune activity.
GDC-0199 is a small-molecule Bcl-2 inhibitor. Find out how inhibiting Bcl-2 may elicit cancer cell apoptosis.
Cobimetinib is a potent inhibitor of MEK activity. Learn more about how targeting MEK may help overcome activating mutations upstream in the MAPK cascade.
Onartuzumab is a monovalent antibody designed to bind to and block activation of MET. Learn how blockade of MET may inhibit cancer cell growth, survival, and metastasis.
Learn more about how the anti-EGFL7 antibody may inhibit critical cellular processes associated with tumor angiogenesis.
PI3K-alpha Inhibitor (GDC-0032)
Learn more about how GDC-0032 may affect tumor cell growth and regression by inhibiting PI3Kα.
Learn more about how pictilisib may affect tumor cell growth and viability by inhibiting PI3K signaling.
PI3K/mTOR Inhibitor (GDC-0980)
Learn more about how the dual blockade of mTOR and PI3K may lead to growth arrest and apoptosis in cancer cells.