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This figure was adapted with permission from Cell, Vol 100, Hanahan and Weinberg, The Hallmarks of Cancer, pp 57-70, Copyright Elsevier (2000).
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Cell Growth Signaling
This figure was adapted with permission from Cell, Vol 100, Hanahan and Weinberg, The Hallmarks of Cancer, pp 57-70, Copyright Elsevier (2000).
Growth signaling:
- Self-sufficiency in growth signals: Cancer cells produce their own growth signals and proliferate without environmental cues1
- Insensitivity to antigrowth signals: Cancer cells evade antigrowth signals in order to proliferate1
Reference:
- 1.
- Hanahan D, Weinberg RA. The hallmarks of cancer. Cell. 2000;100:57-70.