Dedicated to Rigorous and Groundbreaking Science
As a result of our commitment to basic research, Genentech, a member of the Roche Group, has a robust product pipeline, with innovative compounds designed to target cancer through specific molecular processes.
Select any of the research areas below to learn more:
Angiogenesis is a vital process that facilitates tumor growth and survival. Learn more about key signaling and components that promote tumor angiogenesis.
Apoptosis is vital for cellular homeostasis. Learn more about how dysregulation of this critical process leads to tumor growth.
B-cell Surface Proteins
Learn more about major B-cell surface proteins that are implicated in a multitude of hematologic malignancies.
Explore the HER pathways and their role in cancer biology.
MAPK signaling plays a vital role in cell growth and proliferation. Learn more about the consequences of dysregulated MAPK signaling in cancer cells.
Learn more about the mechanism of Met signaling and its effects on tumor cell proliferation, adhesion/motility/invasion, and survival.
Learn more about various molecular components of the PI3K signaling cascade that promote tumor cell growth and survival.
See how this form of cellular internalization can deliver extracellular molecules directly to target cells.